Ethyl Acetate → HCID 70546750, compound

HRID 2059101Notes

Reaction equation

HRID 2059101 reaction equation
[OH:1][CH:2]([CH:26]1[CH2:31][C:30]([CH3:33])([CH3:32])[NH:29][C:28]([CH3:35])([CH3:34])[CH2:27]1)[CH2:3][NH:4][C:5]1[N:10]=[C:9]([NH:11][CH2:12][CH:13]([CH:15]2[CH2:20][C:19]([CH3:22])([CH3:21])[NH:18][C:17]([CH3:24])([CH3:23])[CH2:16]2)[OH:14])[N:8]=[C:7](Cl)[N:6]=1.[CH2:36]([NH2:48])[CH2:37][CH2:38][CH2:39][CH2:40][CH2:41][CH2:42][CH2:43][CH2:44][CH2:45][CH2:46][CH3:47].C(OCC)(=O)C>CO>[OH:1][CH:2]([CH:26]1[CH2:31][C:30]([CH3:33])([CH3:32])[NH:29][C:28]([CH3:35])([CH3:34])[CH2:27]1)[CH2:3][NH:4][C:5]1[N:10]=[C:9]([NH:11][CH2:12][CH:13]([CH:15]2[CH2:20][C:19]([CH3:22])([CH3:21])[NH:18][C:17]([CH3:24])([CH3:23])[CH2:16]2)[OH:14])[N:8]=[C:7]([NH:48][CH2:36][CH2:37][CH2:38][CH2:39][CH2:40][CH2:41][CH2:42][CH2:43][CH2:44][CH2:45][CH2:46][CH3:47])[N:6]=1

Participants

5

Reactant 3

HCID 8857Ethyl AcetateHCID 13583DodecylamineHCID 867383042,4-Bis{2-hydroxy-N-(2,2,6,6-tetramethyl-4-piperidyl)ethylamino}-6-chloro-1,3,5-triazine

Product 1

HCID 70546750HCID 70546750, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

Following the procedure of Example 1, 2,4-bis{2-hydroxy-N-(2,2,6,6-tetramethyl-4-piperidyl)ethylamino}-6-chloro-1,3,5-triazine (5.2 g) was reacted with dodecylamine (2.8 g) to afford an oily product. It was treated with alumina column chromatography (eluent=ethyl acetate:methanol=10:1) and the resulting crystals were recrystallized from n-hexane to afford the desired product as white crystals melting at 107°-109° C.

Workup

  1. customto afford an oily product
  2. customthe resulting crystals were recrystallized from n-hexane

Sources & evidence

ORD record
ord-7b265cb73dad46e2bf75b8b937195dd9
Source dataset
uspto-grants-1982_03
Patent number
US04321374

Reaction notes

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