Sodium Iodide → HCID 13037120, compound

HRID 2059354Notes

Reaction equation

HRID 2059354 reaction equation
Cl[CH2:2][CH:3]([OH:12])[CH2:4][O:5][C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][CH:7]=1.[I-:13].[Na+]>CC(C)=O>[I:13][CH2:2][C@@H:3]([OH:12])[CH2:4][O:5][C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][CH:7]=1

Participants

4

Reactant 2

HCID 5238Sodium IodideHCID 943001-Chloro-3-phenoxy-2-propanol

Product 1

HCID 13037120HCID 13037120, compound

Reagents, catalysts & solvents 1

HCID 180AcetoneSolvent

Procedure

A mixture of 55 g (0.29 mol) of 1-chloro-2-hydroxy-3-phenoxypropane, 170 g (1.1 mol) sodium iodide in 1.0 of acetone is refluxed in the dark under a nitrogen atmosphere for 3 days. The acetone is removed in vacuo, the residue slurried in chloroform, filtered and the filtrate stripped to afford the title compound.

Workup

  1. temperatureis refluxed in the dark under a nitrogen atmosphere for 3 days
  2. customThe acetone is removed in vacuo
  3. filtrationfiltered

Sources & evidence

ORD record
ord-b7314cbcc7e3438baf97e853cebd289e
Source dataset
uspto-grants-1982_03
Patent number
US04322557

Reaction notes

Loading…