Chloride → tert-butyl 4-(5-methoxy-1-methyl-1H-pyrrolo[3,2-b]pyridin-6-yl)-5,6-dihydropyridine-1(2H)-carboxylate

HRID 206076Notes

Reaction equation

HRID 206076 reaction equation
[CH2:46]1[O:47][CH2:48][CH2:49][O:50][CH2:51]1.[CH3:1][O:2][c:3]1[c:4]([B:13]([OH:14])[OH:15])[cH:5][c:6]2[c:7]([n:8]1)[cH:9][cH:10][n:11]2[CH3:12].[Cl-:23].[F:24][C:25]([F:26])([F:27])[S:28]([O:29][C:30]1=[CH:31][CH2:32][N:33]([C:36](=[O:37])[O:38][C:39]([CH3:40])([CH3:41])[CH3:42])[CH2:34][CH2:35]1)(=[O:43])=[O:44].[Li+:22].[Na+:16].[Na+:17].[O-:18][C:19](=[O:20])[O-:21].[OH2:45]>>[CH3:1][O:2][c:3]1[c:4]([C:30]2=[CH:31][CH2:32][N:33]([C:36](=[O:37])[O:38][C:39]([CH3:40])([CH3:41])[CH3:42])[CH2:34][CH2:35]2)[cH:5][c:6]2[c:7]([n:8]1)[cH:9][cH:10][n:11]2[CH3:12]

Participants

9

Reactant 8

HCID 312ChlorideHCID 923Sodium ion2×HCID 962WaterHCID 19660Carbonate IonHCID 28486Lithium ionHCID 312751,4-DioxaneHCID 10991161Tert-butyl 4-(trifluoromethanesulfonyloxy)-1,2,3,6-tetrahydropyridine-1-carboxylateHCID 59006378B-(5-methoxy-1-methyl-1h-pyrrolo[3,2-b]pyridin-6-yl)-boronic acid

Product 1

HCID 59006345tert-butyl 4-(5-methoxy-1-methyl-1H-pyrrolo[3,2-b]pyridin-6-yl)-5,6-dihydropyridine-1(2H)-carboxylate

Sources & evidence

ORD record
ord-3b6225d307bd4d70b0c79e4b639a9587
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

Loading…