1-Methylpyrrolidine → cis-N-(2,8-bis(trifluoromethyl)quinolin-4-yl)-N'-(7-chloroquinolin-4-yl)cyclohexane-1,4-diamine
Reaction equation
[CH3:39][CH2:40][N:41]([CH2:42][CH3:43])[CH2:44][CH3:45].[CH3:46][N:47]1[CH2:48][CH2:49][CH2:50][CH2:51]1.[Cl:1][c:2]1[cH:3][cH:4][c:5]2[c:6]([NH:12][CH:13]3[CH2:14][CH2:15][CH:16]([NH2:19])[CH2:17][CH2:18]3)[cH:7][cH:8][n:9][c:10]2[cH:11]1.[Cl:20][c:21]1[cH:22][c:23]([C:35]([F:36])([F:37])[F:38])[n:24][c:25]2[c:26]([C:31]([F:32])([F:33])[F:34])[cH:27][cH:28][cH:29][c:30]12>>[Cl:1][c:2]1[cH:3][cH:4][c:5]2[c:6]([NH:12][CH:13]3[CH2:14][CH2:15][CH:16]([NH:19][c:21]4[cH:22][c:23]([C:35]([F:36])([F:37])[F:38])[n:24][c:25]5[c:26]([C:31]([F:32])([F:33])[F:34])[cH:27][cH:28][cH:29][c:30]45)[CH2:17][CH2:18]3)[cH:7][cH:8][n:9][c:10]2[cH:11]1Participants
5
Sources & evidence
- ORD record
- ord-f926bf4de1424b658f3087959fd2a010
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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