反应详情

To a solution of 19 (50 mg, 0.16 mmol) in EtOH (1.0 mL), benzohydrazide (26 mg, 0.19 mmol) was added and stirred at rt for 2 h. The solvent was removed under vacuum to yield crude 2-benzoyl-N-(3-(1,7-dimethyl-2-oxo-1,2-dihydro-1,6-naphthyridin-3-yl)-4-methylphenyl)hydrazinecarbothioamide, which was used without purification. MS m/z 458.2 (M+1).

1. customThe solvent was removed under vacuum