Sodium periodate → HCID 59268863, compound

HRID 2061617Notes

Reaction equation

HRID 2061617 reaction equation
I([O-])(=O)(=O)=O.[Na+].[O:7]1[C:11]2[CH:12]=[CH:13][C:14]([CH:16]3[CH2:20][CH:19]([OH:21])[CH:18]([OH:22])[CH2:17]3)=[CH:15][C:10]=2[O:9][CH2:8]1>C1COCC1.O>[O:7]1[C:11]2[CH:12]=[CH:13][C:14]([CH:16]([CH2:20][CH:19]=[O:21])[CH2:17][CH:18]=[O:22])=[CH:15][C:10]=2[O:9][CH2:8]1

Participants

5

Reactant 2

HCID 23667635Sodium periodateHCID 59268872HCID 59268872, compound

Product 1

HCID 59268863HCID 59268863, compound

Reagents, catalysts & solvents 2

HCID 962WaterSolventHCID 8028TetrahydrofuranSolvent

Procedure

To a solution of sodium periodate (1.91 mmol, 0.41 g) in THF (3 mL) and H2O (2 mL) at 0° C. was added diol 99 (1.91 mmol, 0.42 g). The reaction mixture was stirred at room temperature for 3 h. The reaction mixture was filtered, and the resulting dialdehyde 100 was used as is, as an aqueous solution.

Workup

  1. filtrationThe reaction mixture was filtered

Sources & evidence

ORD record
ord-0a4d6b3f4dcb42b0ae68705385c38c66
Source dataset
uspto-grants-2012_10
Patent number
US08283358B2

Reaction notes

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