4-Methylmorpholine → Benzyl 1-{[(4-{[2-(aminocarbonyl)pyridin-4-yl]oxy}-2,5-difluorophenyl)amino]carbonyl}cyclopropanecarboxylate
Reaction equation
[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][C:9](=[O:10])[C:11]1([C:14](=[O:15])[OH:16])[CH2:12][CH2:13]1.[CH3:17][N:18]1[CH2:19][CH2:20][O:21][CH2:22][CH2:23]1.[NH2:28][c:29]1[cH:30][c:31]([F:46])[c:32]([O:33][c:34]2[cH:35][c:36]([C:40](=[O:41])[NH2:42])[n:37][cH:38][cH:39]2)[cH:43][c:44]1[F:45].[O:47]1[CH2:48][CH2:49][CH2:50][CH2:51]1.[S:24]([Cl:25])([Cl:26])=[O:27]>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][C:9](=[O:10])[C:11]1([C:14](=[O:16])[NH:28][c:29]2[cH:30][c:31]([F:46])[c:32]([O:33][c:34]3[cH:35][c:36]([C:40](=[O:41])[NH2:42])[n:37][cH:38][cH:39]3)[cH:43][c:44]2[F:45])[CH2:12][CH2:13]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-42e7a1c2f0ac4d14a6e379f00d5b86c3
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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