反应详情

Pyridinium tosylate (15 mg, 0.06 mmol) and ethyl vinyl ether (339 mg, 450 μl, 4.70 mmol) were added to a solution of 4-(1-hydroxy-2-phenoxyethyl)cyclohexanone (919 mg, 3.92 mmol) in anhydrous methylene chloride (20 ml) and the mixture was stirred at room temperature overnight. Methylene chloride (20 ml) was then added to the mixture and the mixture was washed with water, 5% strength sodium bicarbonate solution and saturated sodium chloride solution (50 ml of each). The organic phase was dried with sodium sulfate and concentrated in vacuo.

1. washthe mixture was washed with water, 5% strength sodium bicarbonate solution and saturated sodium chloride solution (50 ml of each)
2. dry with materialThe organic phase was dried with sodium sulfate
3. concentrationconcentrated in vacuo