1,3-Cyclohexanedione → 2-[(Dimethylamino)methylidene]cyclohexane-1,3-dione

HRID 2063769Notes

Reaction equation

HRID 2063769 reaction equation
[C:1]1(=[O:8])[CH2:6][CH2:5][CH2:4][C:3](=[O:7])[CH2:2]1.[CH3:9][N:10]([CH:12](OC)OC)[CH3:11]>CC#N>[CH3:9][N:10]([CH:12]=[C:2]1[C:3](=[O:7])[CH2:4][CH2:5][CH2:6][C:1]1=[O:8])[CH3:11]

Participants

4

Reactant 2

HCID 104341,3-CyclohexanedioneHCID 78373Dimethylformamide dimethyl acetal

Product 1

HCID 3593532-[(Dimethylamino)methylidene]cyclohexane-1,3-dione

Reagents, catalysts & solvents 1

HCID 6342AcetonitrileSolvent

Procedure

A MeCN solution of cyclohexane-1,3-dione 2.24 g (0.02 mol) i and DMF-DMA 11.9 g (0.1 mol) was stirred at room temperature for 4 h. The solvent was removed under reduced pressure and the product was used for the next step with no purification.

Workup

  1. customThe solvent was removed under reduced pressure
  2. customthe product was used for the next step with no purification

Sources & evidence

ORD record
ord-6bc954deaddd45a7a48765e933f4900b
Source dataset
uspto-grants-2012_10
Patent number
US08288400B2

Reaction notes

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