Dichloromethane → 4-(5-Bromo-isoquinolin-6-yloxy)-piperidine-1-carboxylic acid tert-butyl ester
Reaction equation
[Br:32][c:33]1[c:34]2[cH:35][cH:36][n:37][cH:38][c:39]2[cH:40][cH:41][c:42]1[OH:43].[C:44](=[O:45])([O:46][C:47]([CH3:48])([CH3:49])[CH3:50])[N:51]1[CH2:52][CH2:53][CH:54]([OH:57])[CH2:55][CH2:56]1.[CH2:58]([N:59]([CH2:60][CH3:61])[CH2:62][CH3:63])[CH3:64].[Cl:65][CH2:66][Cl:67].[N:1]([C:2]([O:3][CH2:4][CH3:5])=[O:6])=[N:7][C:8]([O:9][CH2:10][CH3:11])=[O:12].[c:13]1([P:14]([c:15]2[cH:16][cH:17][cH:18][cH:19][cH:20]2)[c:21]2[cH:22][cH:23][cH:24][cH:25][cH:26]2)[cH:27][cH:28][cH:29][cH:30][cH:31]1>>[Br:32][c:33]1[c:34]2[cH:35][cH:36][n:37][cH:38][c:39]2[cH:40][cH:41][c:42]1[O:43][CH:54]1[CH2:53][CH2:52][N:51]([C:44](=[O:45])[O:46][C:47]([CH3:48])([CH3:49])[CH3:50])[CH2:56][CH2:55]1Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-ebb43d63352344b097155eef0489655c
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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