Hydrochloric Acid → HCID 69122201, compound

HRID 2064070Notes

Reaction equation

HRID 2064070 reaction equation
[CH3:1][CH:2]([C:4]1[CH:5]=[CH:6][C:7]2[NH:11][C:10](=[O:12])[N:9]([CH:13]3[CH2:18][CH2:17][N:16](C(OC(C)(C)C)=O)[CH2:15][CH2:14]3)[C:8]=2[CH:26]=1)[CH3:3].[ClH:27]>CO.C(O)C>[ClH:27].[CH3:3][CH:2]([C:4]1[CH:5]=[CH:6][C:7]2[NH:11][C:10](=[O:12])[N:9]([CH:13]3[CH2:14][CH2:15][NH:16][CH2:17][CH2:18]3)[C:8]=2[CH:26]=1)[CH3:1]

Participants

5

Reactant 2

HCID 313Hydrochloric AcidHCID 57423913HCID 57423913, compound

Product 1

HCID 69122201HCID 69122201, compound

Reagents, catalysts & solvents 2

HCID 702EthanolSolventHCID 887MethanolSolvent

Procedure

A solution of 1,1-dimethylethyl 4-[6-(1-methylethyl)-2-oxo-2,3-dihydro-1H-benzimidazol-1-yl]-1-piperidinecarboxylate D34 (0.71 g) in methanol (30 mL) was treated with a saturated solution of hydrogen chloride in ethanol (10 mL). The mixture was stirred for 1 hour when the solvent was removed to give the title compound as a white solid (0.59 g).

Workup

  1. customwas removed

Sources & evidence

ORD record
ord-96b0bcc39b394adbbcbb65b7a31714dd
Source dataset
uspto-grants-2012_10
Patent number
US08288413B2

Reaction notes

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