Iodoethane → HCID 57572007, compound

HRID 2064118Notes

Reaction equation

HRID 2064118 reaction equation
[O:1]1[C:5]2[CH:6]=[CH:7][CH:8]=[C:9]([C:10]3[CH:11]=[C:12]([N:16]4[C:20]5[CH:21]=[CH:22][C:23]([CH:25]([OH:27])[CH3:26])=[CH:24][C:19]=5[N:18]=[CH:17]4)[CH:13]=[CH:14][CH:15]=3)[C:4]=2[O:3][CH2:2]1.[H-].[Na+].[CH2:30](I)[CH3:31]>>[O:1]1[C:5]2[CH:6]=[CH:7][CH:8]=[C:9]([C:10]3[CH:11]=[C:12]([N:16]4[C:20]5[CH:21]=[CH:22][C:23]([CH:25]([O:27][CH2:30][CH3:31])[CH3:26])=[CH:24][C:19]=5[N:18]=[CH:17]4)[CH:13]=[CH:14][CH:15]=3)[C:4]=2[O:3][CH2:2]1

Participants

4

Reactant 3

HCID 6340IodoethaneHCID 24758Sodium hydrideHCID 57572022HCID 57572022, compound

Product 1

HCID 57572007HCID 57572007, compound

Procedure

This was prepared from compound 17 by deprotonisation with sodium hydride followed by alkylation with ethyliodide using standard conditions. LC-ESI-HRMS of [M+H]+ shows 387.1705 Da. Calc. 387.170868 Da, dev. −1 ppm

Sources & evidence

ORD record
ord-4a9c51da4b934000b2eb392f396a9e61
Source dataset
uspto-grants-2012_10
Patent number
US08288418B2

Reaction notes

Loading…