反应详情

1,1-Dimethylethyl 4-(6-chloro-5-methyl-2-oxo-2,3-dihydro-1H-benzimidazol-1-yl)-1-piperidinecarboxylate (D8) (0.270 mmol, 100 mg) was treated with 8 ml of HCl (4M solution in 1,4-dioxane) at room temperature; the mixture was stirred at room temperature for 5 hours. Solvent was evaporated to afford the title compound, mono hydrochloride salt, 60 mg, 90%, M++H=266.

1. customSolvent was evaporated