反应详情

1,1-Dimethylethyl 4-(5-trifluoromethyl-6-chloro-2-oxo-2,3-dihydro-1H-benzimidazol-1-yl)-1-piperidinecarboxylate (D63, 1.0 g) was dissolved in dichloromethane (10 ml) and HCl (4M in 1,4-dioxane, 2.5 ml) was added at room temperature. The mixture was stirred at room temperature for 4 h then evaporated to give the subtitle compound, 850 mg.

1. customthen evaporated