Tetrahydrofuran → 1-(cyclopropylmethyl)-2-(4-ethoxybenzyl)-N-methyl-1H-benzimidazol-5-amine
Reaction equation
[Al+3:30].[CH2:35]1[O:36][CH2:37][CH2:38][CH2:39]1.[CH:1]1([CH2:4][n:5]2[c:6]([CH2:19][c:20]3[cH:21][cH:22][c:23]([O:26][CH2:27][CH3:28])[cH:24][cH:25]3)[n:7][c:8]3[c:9]2[cH:10][cH:11][c:12]([NH:14][C:15](=[O:16])[O:17][CH3:18])[cH:13]3)[CH2:2][CH2:3]1.[H-:29].[H-:32].[H-:33].[H-:34].[Li+:31]>>[CH:1]1([CH2:4][n:5]2[c:6]([CH2:19][c:20]3[cH:21][cH:22][c:23]([O:26][CH2:27][CH3:28])[cH:24][cH:25]3)[n:7][c:8]3[c:9]2[cH:10][cH:11][c:12]([NH:14][CH3:15])[cH:13]3)[CH2:2][CH2:3]1Participants
6
Sources & evidence
- ORD record
- ord-64a04bacb285415a98041f5f546365cf
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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