1,2-Dichloroethane → 7-amino-2-methyl-4-[trans-4-(4-methylpiperazin-1-yl)cyclohexyl]-2,3-dihydro-1H-isoindol-1-one
Reaction equation
[C:27]([O:28][BH-:29]([O:30][C:31](=[O:32])[CH3:33])[O:34][C:35](=[O:36])[CH3:37])(=[O:38])[CH3:39].[CH3:20][N:21]1[CH2:22][CH2:23][NH:24][CH2:25][CH2:26]1.[Cl:41][CH2:42][CH2:43][Cl:44].[NH2:1][c:2]1[cH:3][cH:4][c:5]([CH:13]2[CH2:14][CH2:15][C:16](=[O:19])[CH2:17][CH2:18]2)[c:6]2[c:10]1[C:9](=[O:11])[N:8]([CH3:12])[CH2:7]2.[Na+:40]>>[NH2:1][c:2]1[cH:3][cH:4][c:5]([CH:13]2[CH2:14][CH2:15][CH:16]([N:24]3[CH2:23][CH2:22][N:21]([CH3:20])[CH2:26][CH2:25]3)[CH2:17][CH2:18]2)[c:6]2[c:10]1[C:9](=[O:11])[N:8]([CH3:12])[CH2:7]2Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-60734b0f238e4161993a8c6cd7a552ee
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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