Hydrochloric Acid → 1-[2-[3-(4-Trifluoromethyl-phenyl)-1-(3-isopropoxy-benzoyl)-pyrrolidin-3-yl]-ethyl]-4-phenyl-piperidine-4-carboxylic acid amide
Reaction equation
[CH2:53]1[O:54][CH2:55][CH2:56][CH2:57]1.[ClH:31].[F:1][C:2]([c:3]1[cH:4][cH:5][c:6]([C:9]2([CH2:26][CH2:27][Br:28])[CH2:10][N:11]([C:14]([c:15]3[cH:16][c:17]([O:21][CH:22]([CH3:23])[CH3:24])[cH:18][cH:19][cH:20]3)=[O:25])[CH2:12][CH2:13]2)[cH:7][cH:8]1)([F:29])[F:30].[K+:47].[K+:48].[O-:49][C:50]([O-:51])=[O:52].[OH2:58].[c:32]1([C:38]2([C:44](=[O:45])[NH2:46])[CH2:39][CH2:40][NH:41][CH2:42][CH2:43]2)[cH:33][cH:34][cH:35][cH:36][cH:37]1>>[F:1][C:2]([c:3]1[cH:4][cH:5][c:6]([C:9]2([CH2:26][CH2:27][N:41]3[CH2:40][CH2:39][C:38]([c:32]4[cH:33][cH:34][cH:35][cH:36][cH:37]4)([C:44](=[O:45])[NH2:46])[CH2:43][CH2:42]3)[CH2:10][N:11]([C:14]([c:15]3[cH:16][c:17]([O:21][CH:22]([CH3:23])[CH3:24])[cH:18][cH:19][cH:20]3)=[O:25])[CH2:12][CH2:13]2)[cH:7][cH:8]1)([F:29])[F:30]Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-9ea1eff6e4c34368a6bf2aa8c1e32ad4
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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