Ammonia → 3-Bromo-1-(4-phenoxyphenyl)-imidazo[1,5-a]pyrazin-8-ylamine

HRID 206892Notes

Reaction equation

HRID 206892 reaction equation
[Br:1][c:2]1[n:3][c:4](-[c:12]2[cH:13][cH:14][c:15]([O:18][c:19]3[cH:20][cH:21][cH:22][cH:23][cH:24]3)[cH:16][cH:17]2)[c:5]2[n:6]1[cH:7][cH:8][n:9][c:10]2[Cl:11].[CH:26]([OH:27])([CH3:28])[CH3:29].[CH:30]([O:31][CH:32]([CH3:33])[CH3:34])([CH3:35])[CH3:36].[NH3:25]>>[Br:1][c:2]1[n:3][c:4](-[c:12]2[cH:13][cH:14][c:15]([O:18][c:19]3[cH:20][cH:21][cH:22][cH:23][cH:24]3)[cH:16][cH:17]2)[c:5]2[n:6]1[cH:7][cH:8][n:9][c:10]2[NH2:25]

Participants

5

Reactant 4

HCID 222AmmoniaHCID 3776IsopropanolHCID 7914Diisopropyl EtherHCID 866360333-Bromo-8-chloro-1-(4-phenoxy-phenyl)-imidazo[1,5-a]pyrazine

Product 1

HCID 669155513-Bromo-1-(4-phenoxyphenyl)-imidazo[1,5-a]pyrazin-8-ylamine

Sources & evidence

ORD record
ord-9281eecfde674b4f84b530bb4c2c13d8
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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