Toluene → 1-((2-(Trifluoromethyl)phenyl)methyl)piperazine
Reaction equation
[Br:7][CH2:8][c:9]1[c:10]([C:15]([F:16])([F:17])[F:18])[cH:11][cH:12][cH:13][cH:14]1.[CH2:1]1[CH2:2][NH:3][CH2:4][CH2:5][NH:6]1.[CH3:19][CH2:20][N:21]([CH2:22][CH3:23])[CH2:24][CH3:25].[CH3:26][c:27]1[cH:28][cH:29][cH:30][cH:31][cH:32]1>>[CH2:1]1[CH2:2][N:3]([CH2:8][c:9]2[c:10]([C:15]([F:16])([F:17])[F:18])[cH:11][cH:12][cH:13][cH:14]2)[CH2:4][CH2:5][NH:6]1Participants
5
Sources & evidence
- ORD record
- ord-1a6fdde456054b799ab35eabd762acdc
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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