(-)-Glycidol → HCID 178436631, compound

HRID 2069406Notes

Reaction equation

HRID 2069406 reaction equation
[CH2:1]([C:3]1[CH:18]=[C:17]([C:19](=[NH:22])[NH:20][OH:21])[CH:16]=[C:15]([CH3:23])[C:4]=1[O:5][CH2:6][C@@H:7]([OH:14])[CH2:8][NH:9][C:10](=[O:13])[CH2:11][OH:12])[CH3:2].C(C1C=C(C=C(C)C=1O)C#N)C.C1O[C@H]1CO>>[CH2:1]([C:3]1[CH:18]=[C:17]([C:19](=[NH:22])[NH:20][OH:21])[CH:16]=[C:15]([CH3:23])[C:4]=1[O:5][CH2:6][C@H:7]([OH:14])[CH2:8][NH:9][C:10](=[O:13])[CH2:11][OH:12])[CH3:2]

Participants

4

Reactant 3

HCID 6973630(-)-GlycidolHCID 597599503-Ethyl-4-hydroxy-5-methylbenzonitrileHCID 178436630HCID 178436630, compound

Product 1

HCID 178436631HCID 178436631, compound

Procedure

The title compound is obtained as a yellow oil (1.36 g) in analogy to N—((S)-3-[2-ethyl-4-(N-hydroxycarbamimidoyl)-6-methyl-phenoxy]-2-hydroxy-propyl)-2-hydroxy-acetamide starting from 3-ethyl-4-hydroxy-5-methyl-benzonitrile and (S)-glycidol; LC-MS: tR=0.51 min, [M+H]+=326.00.

Sources & evidence

ORD record
ord-3c17301a1e2e452b83432f465eafed48
Source dataset
uspto-grants-2012_10
Patent number
US08299086B2

Reaction notes

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