Potassium Acetate → HCID 24849296, compound

HRID 20706Notes

Reaction equation

HRID 20706 reaction equation
[C:1]([O-:4])(=[O:3])[CH3:2].[K+].Br[CH2:7][CH2:8][CH2:9][CH2:10][O:11][C:12]1[C:13]([O:32][CH3:33])=[CH:14][CH:15]=[C:16]2[C:21]=1[O:20][C:19](=[O:22])[CH:18]=[C:17]2[NH:23][C:24]1[C:29]([Cl:30])=[CH:28][N:27]=[CH:26][C:25]=1[Cl:31]>>[C:1]([O:4][CH2:7][CH2:8][CH2:9][CH2:10][O:11][C:12]1[C:13]([O:32][CH3:33])=[CH:14][CH:15]=[C:16]2[C:21]=1[O:20][C:19](=[O:22])[CH:18]=[C:17]2[NH:23][C:24]1[C:25]([Cl:31])=[CH:26][N:27]=[CH:28][C:29]=1[Cl:30])(=[O:3])[CH3:2]

Participants

3

Reactant 2

HCID 517044Potassium AcetateHCID 248495678-(4-bromobutoxy)-4-(3,5-dichloropyridin-4-ylamino)-7-methoxy-2H-chromen-2-one

Product 1

HCID 24849296HCID 24849296, compound

Procedure

The title compound can be prepared from potassium acetate and 8-(4-bromobutoxy)-4-(3,5-dichloropyridin-4-ylamino)-7-methoxy-2H-chromen-2-one (Example 25) following the procedure outlined in Example 52. 1H NMR (400 MHz, CD3OD): δ 8.70 (s, 2H), 7.84 (d, 1H), 7.16 (d, 1H), 4.77 (s, 1H), 4.16 (t, 2H), 4.11 (t, 2H), 3.98 (s, 3H), 2.02 (s, 3H), 1.91 (m, 2H), 1.84 (m, 2H); MS (ESI): 466.9.

Sources & evidence

ORD record
ord-a20790e18be94667a8d9e99f9f95ce8c
Source dataset
uspto-grants-2010_06
Patent number
US07745646B2

Reaction notes

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