HCID 87536207, compound → (1H-Indol-7-YL)methanamine

HRID 2070985Notes

Reaction equation

HRID 2070985 reaction equation
[NH:1]1[C:9]2[C:4](=[CH:5][CH:6]=[CH:7][C:8]=2/[CH:10]=[N:11]\O)[CH:3]=[CH:2]1>CO.[OH-].[OH-].[Pd+2]>[NH:1]1[C:9]2[C:4](=[CH:5][CH:6]=[CH:7][C:8]=2[CH2:10][NH2:11])[CH:3]=[CH:2]1

Participants

4

Reactant 1

HCID 87536207HCID 87536207, compound

Product 1

HCID 21950026(1H-Indol-7-YL)methanamine

Reagents, catalysts & solvents 2

HCID 9942167Palladium hydroxideCatalystHCID 887MethanolSolvent

Procedure

(Z)-1H-indole-7-carbaldehyde oxime (100 mg, 0.60 mmol) in MeOH (5 mL), Pd(OH)2 (50 mg) was added and stirred under hydrogen atmosphere (balloon pressure) for 4 h. Reaction mixture was then filtered and solvent evaporated to yield (1H-indol-7-yl)methanamine in quantitative yield.

Workup

  1. customReaction mixture
  2. filtrationwas then filtered
  3. customsolvent evaporated

Sources & evidence

ORD record
ord-9a620c84e1084ad08c247bf65c816272
Source dataset
uspto-grants-2012_10
Patent number
US08299267B2

Reaction notes

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