4-{[(2,2-Dichlorocyclopropyl)methyl]sulfanyl}-2-nitroaniline → HCID 20532837, compound

HRID 2071430Notes

Reaction equation

HRID 2071430 reaction equation
[Cl:1][C:2]1([Cl:17])[CH2:4][CH:3]1[CH2:5][S:6][C:7]1[CH:13]=[CH:12][C:10]([NH2:11])=[C:9]([N+:14]([O-])=O)[CH:8]=1>C(O)C.O=[Pt]=O>[Cl:17][C:2]1([Cl:1])[CH2:4][CH:3]1[CH2:5][S:6][C:7]1[CH:13]=[CH:12][C:10]([NH2:11])=[C:9]([NH2:14])[CH:8]=1

Participants

4

Reactant 1

HCID 205328394-{[(2,2-Dichlorocyclopropyl)methyl]sulfanyl}-2-nitroaniline

Product 1

HCID 20532837HCID 20532837, compound

Reagents, catalysts & solvents 2

HCID 345198Adams' catalystCatalystHCID 702EthanolSolvent

Procedure

A mixture of 8.8 g (0.03 mole) of 4-[(2,2-dichlorocyclopropyl)methyl]thio-2-nitroaniline and 0.6 g of PtO2 in 200 ml of absolute ethanol is reduced on the Parr hydrogenator at 50 psi until the theoretical amount of H2 is absorbed. The mixture is filtered and the solvent is removed in vacuo to yield a dark oil.

Workup

  1. customis absorbed
  2. filtrationThe mixture is filtered
  3. customthe solvent is removed in vacuo
  4. customto yield a dark oil

Sources & evidence

ORD record
ord-7439281ecbd54d4fa2c5e3e5f497e190
Source dataset
uspto-grants-1977_09
Patent number
US04046908

Reaction notes

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