Potassium Carbonate → HCID 21412029, compound

HRID 2071667Notes

Reaction equation

HRID 2071667 reaction equation
C[O:2][C:3](=[O:25])[CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH:11]1[CH2:15][CH2:14][CH:13]([CH2:16][CH2:17][C:18](=[O:24])[CH2:19][CH2:20][CH2:21][CH2:22][CH3:23])[O:12]1.C(=O)([O-])[O-].[K+].[K+]>CO>[O:24]=[C:18]([CH2:19][CH2:20][CH2:21][CH2:22][CH3:23])[CH2:17][CH2:16][CH:13]1[O:12][CH:11]([CH2:10][CH2:9][CH2:8][CH2:7][CH2:6][CH2:5][CH2:4][C:3]([OH:25])=[O:2])[CH2:15][CH2:14]1

Participants

4

Reactant 2

HCID 11430Potassium CarbonateHCID 54381353HCID 54381353, compound

Product 1

HCID 21412029HCID 21412029, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

VIII (1.77 g, 0.00500 mole), methanol (20 ml), and 20% aqueous potassium carbonate (10 ml) were stirred and heated under reflux for 2.5 hours. The methanol was removed fron a water bath (60° C, 100 mm Hg). The residue was diluted with water (25 ml) and washed with ether (25 ml). The resulting clear solution was acidified to pH 5-6 with acetic acid. The emulsion being formed was extracted with ether (25 + 25 ml). The combined ethereal extracts were dried over sodium sulfate and evaporated from a water bath (60° C, 1 mm Hg). The yellowish, oily residue of IX (1.60 g, 94%) solidified by standing. M.p. 26°-28° C, nD25 1.4673.

Workup

  1. temperatureheated
  2. temperatureunder reflux for 2.5 hours
  3. customThe methanol was removed fron a water bath (60° C, 100 mm Hg)
  4. additionThe residue was diluted with water (25 ml)
  5. washwashed with ether (25 ml)
  6. customThe emulsion being formed
  7. extractionwas extracted with ether (25 + 25 ml)
  8. dry with materialThe combined ethereal extracts were dried over sodium sulfate
  9. customevaporated from a water bath (60° C, 1 mm Hg)

Sources & evidence

ORD record
ord-34382c98225c4a68983d267354a6526c
Source dataset
uspto-grants-1977_09
Patent number
US04048198

Reaction notes

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