Ammonium → 4-(2-Ethyl-3-hydroxy-4-methyl-5-oxopyrrolidin-1-yl)-2-(trifluoromethyl)benzonitrile
Reaction equation
[CH2:14]([Li:15])[CH2:16][CH2:17][CH3:18].[CH2:19]([CH3:20])[CH:21]1[N:22]([c:28]2[cH:29][c:30]([C:36]([F:37])([F:38])[F:39])[c:31]([C:32]#[N:33])[cH:34][cH:35]2)[C:23](=[O:27])[CH2:24][CH:25]1[OH:26].[CH3:8][CH2:9][CH2:10][CH2:11][CH2:12][CH3:13].[CH:1]([NH:2][CH:3]([CH3:4])[CH3:5])([CH3:6])[CH3:7].[Cl-:42].[I:40][CH3:41].[NH4+:43].[O:44]1[CH2:45][CH2:46][CH2:47][CH2:48]1>>[CH3:1][CH:24]1[C:23](=[O:27])[N:22]([c:28]2[cH:29][c:30]([C:36]([F:37])([F:38])[F:39])[c:31]([C:32]#[N:33])[cH:34][cH:35]2)[CH:21]([CH2:19][CH3:20])[CH:25]1[OH:26]Participants
9
Reactant 8
Product 1
Sources & evidence
- ORD record
- ord-fd829e26e10546c2831286d956991164
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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