Ammonium → 4-(2-(5-(1,3-Dioxan-2-yl)pyridin-2-yl)thieno[3,2-b]pyridin-7-yloxy)-3-fluoroaniline

HRID 207173Notes

Reaction equation

HRID 207173 reaction equation
[CH3:35][CH2:36][OH:37].[Cl-:33].[Fe:39].[NH4+:34].[O:1]1[CH:2]([c:7]2[cH:8][cH:9][c:10](-[c:13]3[cH:14][c:15]4[n:16][cH:17][cH:18][c:19]([O:22][c:23]5[c:24]([F:32])[cH:25][c:26]([N+:29]([O-:30])=[O:31])[cH:27][cH:28]5)[c:20]4[s:21]3)[n:11][cH:12]2)[O:3][CH2:4][CH2:5][CH2:6]1.[OH2:38]>>[O:1]1[CH:2]([c:7]2[cH:8][cH:9][c:10](-[c:13]3[cH:14][c:15]4[n:16][cH:17][cH:18][c:19]([O:22][c:23]5[c:24]([F:32])[cH:25][c:26]([NH2:29])[cH:27][cH:28]5)[c:20]4[s:21]3)[n:11][cH:12]2)[O:3][CH2:4][CH2:5][CH2:6]1

Participants

7

Reactant 6

HCID 223AmmoniumHCID 312ChlorideHCID 702EthanolHCID 962WaterHCID 23925IronHCID 252122432-(5-(1,3-Dioxan-2-yl)pyridin-2-yl)-7-(2-fluoro-4-nitrophenoxy)thieno[3,2-b]pyridine

Product 1

HCID 579672584-(2-(5-(1,3-Dioxan-2-yl)pyridin-2-yl)thieno[3,2-b]pyridin-7-yloxy)-3-fluoroaniline

Sources & evidence

ORD record
ord-01763a2e28d8476ea03ddb8ffd4c623d
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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