Thionyl Chloride → HCID 178514631, compound

HRID 2072182Notes

Reaction equation

HRID 2072182 reaction equation
[N:1]#[N:2].[C:3]1([S:13]([NH:16][C@H:17]([C:25](O)=[O:26])[CH2:18][CH2:19][CH2:20][NH:21][C:22](=[NH:24])[NH2:23])(=[O:15])=[O:14])[C:12]2[C:7](=[CH:8][CH:9]=[CH:10][CH:11]=2)[CH:6]=[CH:5][CH:4]=1.S(Cl)(Cl)=O.P(Cl)(Cl)(Cl)=O.P(Cl)(Cl)Cl.P(Cl)(Cl)(Cl)(Cl)Cl.P(Br)(Br)Br>>[N:1]#[N:2].[C:3]1([S:13]([NH:16][C@H:17]([C:25]([NH2:1])=[O:26])[CH2:18][CH2:19][CH2:20][NH:21][C:22](=[NH:24])[NH2:23])(=[O:15])=[O:14])[C:12]2[C:7](=[CH:8][CH:9]=[CH:10][CH:11]=2)[CH:6]=[CH:5][CH:4]=1

Participants

7

Reactant 6

HCID 24386Thionyl ChlorideHCID 24387Phosphorus trichlorideHCID 24614Phosphorus tribromideHCID 24813Phosphorus oxychlorideHCID 24819Phosphorus pentachlorideHCID 178514632HCID 178514632, compound

Product 1

HCID 178514631HCID 178514631, compound

Procedure

An N2 -naphthalenesulfonyl-L-argininamide is prepared by reaction of a corresponding N2 -naphthalenesulfonyl-L-arginyl halide and an amine. The N2 -naphthalenesulfonyl-L-arginyl halide is prepared by reacting a corresponding N2 -naphthalenesulfonyl-L-arginine with a halogenating agent such as thionyl chloride, phosphorus oxychloride, phosphorus trichloride, phosphorus pentachloride, phosphorus tribromide, etc.

Sources & evidence

ORD record
ord-8e10455f557c4690be1c92328ea48f07
Source dataset
uspto-grants-1977_09
Patent number
US04049645

Reaction notes

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