Potassium Carbonate → HCID 21408043, compound

HRID 2072323Notes

Reaction equation

HRID 2072323 reaction equation
Br[C:2]([CH3:6])([CH3:5])[CH2:3][OH:4].[Cl:7][C:8]1[CH:22]=[CH:21][C:11]([O:12][CH2:13][C:14]2[CH:19]=[CH:18][C:17]([OH:20])=[CH:16][CH:15]=2)=[CH:10][CH:9]=1.C([O-])([O-])=O.[K+].[K+]>CC(C)=O>[Cl:7][C:8]1[CH:9]=[CH:10][C:11]([O:12][CH2:13][C:14]2[CH:19]=[CH:18][C:17]([O:20][C:2]([CH3:6])([CH3:5])[CH2:3][OH:4])=[CH:16][CH:15]=2)=[CH:21][CH:22]=1

Participants

5

Reactant 3

HCID 11430Potassium CarbonateHCID 14119276HCID 14119276, compoundHCID 234586692-bromo-2-methylpropan-1-ol

Product 1

HCID 21408043HCID 21408043, compound

Reagents, catalysts & solvents 1

HCID 180AcetoneSolvent2×

Procedure

A solution of 15.3 g. of 2-bromo-2-methylpropanol in 50 ml. of acetone is added slowly to a stirred mixture consisting of 23.45 g. of 4-p-chlorophenoxymethyl-phenol, 13.8 g. of K2CO3 an 80 ml. of acetone. The mixture is boiled for 12 hours while stirring and then filtered and evaporated to give 2-[4-(4-chlorophenoxymethyl)-phenoxy]-2-methyl-propanol, m.p. 67°-70° C.

Workup

  1. filtrationfiltered
  2. customevaporated

Sources & evidence

ORD record
ord-35b3e95274d84250a32ab063e112c69a
Source dataset
uspto-grants-1977_09
Patent number
US04051173

Reaction notes

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