反应详情

0.2 mol of 3-formylamino-5-trifluoromethylindazole and 0.05 mol of dimethylcarbamic acid chloride in 20 ml of pyridine are heated for 4 hours to 50° C. After cooling, 150 ml of water are allowed to run in and the reaction product which has crystallized out is isolated by filtration. Recrystallization from ethanol gives 3formylamino-5-trifluoromethylindazole-1-carboxylic acid dimethylamide (melting point: 198°-200° C; 57% of theory).

1. temperatureAfter cooling
2. customhas crystallized out
3. customis isolated by filtration
4. customRecrystallization from ethanol