Hydrochloric Acid → HCID 131710921, compound

HRID 2072506Notes

Reaction equation

HRID 2072506 reaction equation
[CH2:1]1[C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[CH:3]=[C:2]1[CH2:10][N:11]1[CH2:27][CH2:26][C:14]2([N:18]([C:19]3[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=3)[CH2:17][NH:16][C:15]2=[O:25])[CH2:13][CH2:12]1.[ClH:28]>C(O)C>[ClH:28].[CH2:3]1[C:4]2[C:9](=[CH:8][CH:7]=[CH:6][CH:5]=2)[CH:1]=[C:2]1[CH2:10][N:11]1[CH2:27][CH2:26][C:14]2([N:18]([C:19]3[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=3)[CH2:17][NH:16][C:15]2=[O:25])[CH2:13][CH2:12]1

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 214081988-[(1H-Inden-2-yl)methyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one

Product 1

HCID 131710921HCID 131710921, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

8-(1H-Inden-2-ylmethyl)-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one (1.2g) in absolute ethanol (100 ml) is treated with 1.2 equivalents of ethereal hydrogen chloride. Cooling gives the crude hydrochloride salt which is crystallized from absolute ethanol to yield 1.1g of the title compound, melting point 264°-266° C.

Workup

  1. temperatureCooling
  2. customgives the crude hydrochloride salt which
  3. customis crystallized from absolute ethanol

Sources & evidence

ORD record
ord-060f777c1b2c47c0b33aecda80f0a73d
Source dataset
uspto-grants-1977_09
Patent number
US04051248

Reaction notes

Loading…