Chloride → 4-chloro-N-[5-chloro-2-(2-morpholin-4-yl-pyridine-4-carbonyl)-pyridin-3-yl]-N-methoxymethyl-3-trifluoromethyl-benzenesulfonamide

HRID 207293Notes

Reaction equation

HRID 207293 reaction equation
[Br:1][c:2]1[n:3][cH:4][c:5]([Cl:26])[cH:6][c:7]1[N:8]([S:9](=[O:10])(=[O:11])[c:12]1[cH:13][c:14]([C:19]([F:20])([F:21])[F:22])[c:15]([Cl:18])[cH:16][cH:17]1)[CH2:23][O:24][CH3:25].[CH2:50]1[O:51][CH2:52][CH2:53][CH2:54]1.[CH3:32][O:33][N:34]([C:35]([c:36]1[cH:37][c:38]([N:42]2[CH2:43][CH2:44][O:45][CH2:46][CH2:47]2)[n:39][cH:40][cH:41]1)=[O:48])[CH3:49].[CH:28]([Mg+:29])([CH3:30])[CH3:31].[Cl-:27]>>[c:2]1([C:35]([c:36]2[cH:37][c:38]([N:42]3[CH2:43][CH2:44][O:45][CH2:46][CH2:47]3)[n:39][cH:40][cH:41]2)=[O:48])[n:3][cH:4][c:5]([Cl:26])[cH:6][c:7]1[N:8]([S:9](=[O:10])(=[O:11])[c:12]1[cH:13][c:14]([C:19]([F:20])([F:21])[F:22])[c:15]([Cl:18])[cH:16][cH:17]1)[CH2:23][O:24][CH3:25]

Participants

6

Reactant 5

HCID 312ChlorideHCID 8028TetrahydrofuranHCID 57942086N-(2-Bromo-5-chloro-pyridin-3-yl)-4-chloro-N-methoxvmethyl-3-trifluoromethyl-benzenesulfonamideHCID 57942148N-methoxy-N-methyl-2-morpholin-4-yl-isonicotinamideHCID 178461726HCID 178461726, compound

Product 1

HCID 579421674-chloro-N-[5-chloro-2-(2-morpholin-4-yl-pyridine-4-carbonyl)-pyridin-3-yl]-N-methoxymethyl-3-trifluoromethyl-benzenesulfonamide

Sources & evidence

ORD record
ord-97621e8a098a4a10b26d74ed58a9021c
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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