HCID 72744946, compound → HCID 54375492, compound

HRID 2073307Notes

Reaction equation

HRID 2073307 reaction equation
CC(OC(=O)[NH:7][CH:8]([CH3:18])[CH2:9][CH:10]=[CH:11][C:12]1[CH:13]=[N:14][CH:15]=[CH:16][CH:17]=1)(C)C>Cl>[CH3:18][CH:8]([NH2:7])[CH2:9][CH:10]=[CH:11][C:12]1[CH:13]=[N:14][CH:15]=[CH:16][CH:17]=1

Participants

3

Reactant 1

HCID 72744946HCID 72744946, compound

Product 1

HCID 54375492HCID 54375492, compound

Reagents, catalysts & solvents 1

HCID 313Hydrochloric AcidSolvent

Procedure

As in Example 133, hydrolysis of 3.88 g of (R,S)-Z]-[1-methyl-4-(3-Pyridinyl)-3-butenyl]carbamic acid 1,1-dimethylethyl ester in 50 mL of 1N HCl yielded, after the usual work-up and evaporative distillation of the product (100-120° C./0.1 mm), 1.7 g of [(R,S)-Z]-1-methyl-4-(3-pyridinyl)-3-butenamine as an oil.

Workup

  1. customyielded
  2. distillationdistillation of the product (100-120° C./0.1 mm), 1.7 g of [(R,S)-Z]-1-methyl-4-(3-pyridinyl)-3-butenamine as an oil

Sources & evidence

ORD record
ord-3decf60337ba403a832185845aee860e
Source dataset
uspto-grants-1990_04
Patent number
US04916145

Reaction notes

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