Piperidine → HCID 19855906, compound

HRID 2073739Notes

Reaction equation

HRID 2073739 reaction equation
[N:1]([CH2:4][C:5]([C:7]1[CH:12]=[CH:11][C:10]([Cl:13])=[CH:9][C:8]=1[Cl:14])=O)=[N+:2]=[N-:3].[NH:15]1[CH2:20][CH2:19][CH2:18][CH2:17][CH2:16]1.[BH3-]C#N.[Na+]>>[N:1]([CH2:4][CH:5]([N:15]1[CH2:20][CH2:19][CH2:18][CH2:17][CH2:16]1)[C:7]1[CH:12]=[CH:11][C:10]([Cl:13])=[CH:9][C:8]=1[Cl:14])=[N+:2]=[N-:3]

Participants

4

Reactant 3

HCID 8082PiperidineHCID 5003444Sodium cyanoborohydrideHCID 19855941HCID 19855941, compound

Product 1

HCID 19855906HCID 19855906, compound

Procedure

In a manner similar to Preparation 21 react 2-azido-1-(2,4-dichlorophenyl)ethanone with piperidine and NaCNBH3 to obtain the title compound.

Workup

  1. customIn a manner similar to Preparation 21

Sources & evidence

ORD record
ord-e07af38b7dde4fb9b46ab8d12ae9b7ad
Source dataset
uspto-grants-1990_04
Patent number
US04920116

Reaction notes

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