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HRID2073906

反应详情

EQUATION

反应方程式

HRID 2073906 的结构方程式

REACTANTS

反应物

3
结构：O=C([O-])[O-].[K+].[K+]
HCID11430

Potassium Carbonate

CK2O3

结构：ClCc1ccc2ccccc2n1
HCID20394

2-(Chloromethyl)quinoline

C10H8ClN

结构：CCOC(=O)COc1cccc(CC(=O)c2cccc(O)c2)c1
HCID14774136

未命名化合物

PRODUCTS

生成物

1
结构：CCOC(=O)COc1cccc(CC(=O)c2cccc(OCc3ccc4ccccc4n3)c2)c1
HCID14774137

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CN(C)C=O
溶剂HCID6228

N,N-Dimethylformamide

C3H7NO

CONDITIONS

反应条件

温度
60 °C

PROCEDURE

实验过程

A mixture of ethyl 2-(3-(2-(3-hydroxyphenyl)2-oxoethyl)phenoxy)acetate (0.01 mol), 2-chloromethylquinoline (0.01 mol), and K2CO3 (0.01 mol) in 20 mL of DMF are heated at 60° C. overnight. After work-up, the crude product is purified by flash chromatography to give ethyl 2-(3-(2-(3-(2-quinolinylmethyloxy)phenyl)-2-oxoethyl)phenoxy)acetate.

WORKUP

后处理

  1. customAfter work-up, the crude product is purified by flash chromatography