反应详情

温度

60 °C

To a solution of a known compound, 3-(1-ethoxyethylideneaminooxy)-propanoic acid methyl ester (CAS No. 97164-30-2, 41.3 g, 0.218 mol) in methanol (150 ml) was added methylamine (40% solution in methanol, 200 ml) at room temperature, and the mixture was stirred at 60° C. for 12 hours. The reaction mixture was concentrated under reduced pressure to give N-(2-methylcarbamoyl-ethoxy)-acetimidic acid ethyl ester (41.0 g, 100%).

1. concentrationThe reaction mixture was concentrated under reduced pressure