Carbonate Ion → 4-(3-Cyclopropyl-3-hydroxy-2-propan-2-ylpyrrolidin-1-yl)-2-(trifluoromethyl)benzonitrile
Reaction equation
[CH:1]1([C:4]2([OH:12])[CH:5]([CH:9]([CH3:10])[CH3:11])[NH:6][CH2:7][CH2:8]2)[CH2:2][CH2:3]1.[F:13][c:14]1[cH:15][c:16]([C:22]([F:23])([F:24])[F:25])[c:17]([C:18]#[N:19])[cH:20][cH:21]1.[Li+:26].[Li+:27].[O-:28][C:29](=[O:30])[O-:31]>>[CH:1]1([C:4]2([OH:12])[CH:5]([CH:9]([CH3:10])[CH3:11])[N:6]([c:14]3[cH:15][c:16]([C:22]([F:23])([F:24])[F:25])[c:17]([C:18]#[N:19])[cH:20][cH:21]3)[CH2:7][CH2:8]2)[CH2:2][CH2:3]1Participants
5
Sources & evidence
- ORD record
- ord-722fb16813174d569a999f8d8d9f006c
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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