Suberic acid → Oxonane-2,9-dione

HRID 2076419노트

반응식

HRID 2076419 반응식
[C:1]([OH:12])(=[O:11])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][C:8]([OH:10])=O>C(OC(=O)C)(=O)C>[O:12]1[C:1](=[O:11])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][C:8]1=[O:10]

참가 물질

3

반응물 1

HCID 10457Suberic acid

생성물 1

HCID 9543534Oxonane-2,9-dione수율 50.4%

시약·촉매·용매 1

HCID 7918Acetic Anhydride용매

실험 절차

A solution of suberic acid (5.0 g, 28.7 mmol) in acetic anhydride (10 mL) was heated at reflux for 1 h. After cooling to RT, the solvent was removed in vacuo. The pale yellow residue was recrystallized from acetonitrile. After filtration and drying to the vacuum pump, the oxonane-2,9-dione was obtained as a white solid (2.26 g, 50.4% yield).

후처리

  1. temperatureat reflux for 1 h
  2. customthe solvent was removed in vacuo
  3. customThe pale yellow residue was recrystallized from acetonitrile
  4. filtrationAfter filtration
  5. customdrying to the vacuum pump

출처 및 근거

ORD 기록
ord-de2bb5712e94419a90ec52684ee6e963
출처 데이터셋
uspto-grants-2011_04
특허 번호
US07923579B2

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