2-Chloroaniline → HCID 86634852, compound

HRID 2079006Notes

Reaction equation

HRID 2079006 reaction equation
[Cl:1][C:2]1[CH:8]=[CH:7][CH:6]=[CH:5][C:3]=1[NH2:4].[Br:9][C:10]1[CH:11]=[CH:12][C:13]2[O:22][CH2:21][CH2:20][C:19]3[CH:18]=[C:17]([C:23](Cl)=[O:24])[S:16][C:15]=3[C:14]=2[CH:26]=1.C(Cl)(=O)C(Cl)=O>CN(C)C=O>[Cl:1][C:2]1[CH:8]=[CH:7][CH:6]=[CH:5][C:3]=1[NH:4][C:23]([C:17]1[S:16][C:15]2[C:14]3[CH:26]=[C:10]([Br:9])[CH:11]=[CH:12][C:13]=3[O:22][CH2:21][CH2:20][C:19]=2[CH:18]=1)=[O:24]

Participants

5

Reactant 3

HCID 72402-ChloroanilineHCID 65578Oxalyl chlorideHCID 86634853HCID 86634853, compound

Product 1

HCID 86634852HCID 86634852, compound

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

Reaction of 2-chloroaniline with 9-bromo-4,5-dihydro-6-oxa-1-thia-benzo[e]azulene-2-carbonyl chloride (prepared from the corresponding carboxylic acid using oxalyl chloride with catalytic N,N-dimethylformamide) yielded 9-bromo-4,5-dihydro-6-oxa-1-thia-benzo[e]azulene-2-carboxylic acid (2-chloro-phenyl)-amide.

Sources & evidence

ORD record
ord-c86271be236e4ebab90ce3d53e02d85c
Source dataset
uspto-grants-2011_04
Patent number
US07928248B2

Reaction notes

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