Methylamine → HCID 86646580, compound

HRID 2080550Notes

Reaction equation

HRID 2080550 reaction equation
[Cl:1][C:2]1[N:7]=[CH:6][C:5]([CH2:8][N:9]([CH2:16][CH:17]([CH3:19])[CH3:18])[CH2:10][CH2:11][S:12]C(=O)C)=[CH:4][CH:3]=1.CN>C(O)C>[Cl:1][C:2]1[N:7]=[CH:6][C:5]([CH2:8][N:9]([CH2:16][CH:17]([CH3:19])[CH3:18])[CH2:10][CH2:11][SH:12])=[CH:4][CH:3]=1

Participants

4

Reactant 2

HCID 6329MethylamineHCID 86646579HCID 86646579, compound

Product 1

HCID 86646580HCID 86646580, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent2×

Procedure

A mixture of 0.25 gram (0.00083 mole) of 1-(2-{[(6-chloro(3-pyridyl))methyl](2-methylpropyl)-amino}ethylthio)ethan-1-one and 0.78 gram of a 33% solution of methylamine in ethanol (0.0083 mole of methylamine) in 50 mL of ethanol was stirred at ambient temperature two hours. The reaction mixture was concentrated under reduced pressure to a residue. This residue was use without further purification in Step E.

Workup

  1. concentrationThe reaction mixture was concentrated under reduced pressure to a residue
  2. customwithout further purification in Step E

Sources & evidence

ORD record
ord-8052cd8278104b6d87feea7fcf57ae2d
Source dataset
uspto-grants-2011_04
Patent number
US07932393B2

Reaction notes

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