反应详情

温度

70 °C

The compound (83.50 g) obtained in Example 10-2 was suspended in DMF (250 ml) and added with sodium t-butoxide (49.00 g) at −30° C. The solution was further added with a potassium phthalimide salt (95.0 g) and then the whole was stirred at 70° C. for 2 hours. After completion of the reaction, the resultant was added into water (800 ml). The precipitated crystal was filtrated, washed with water, and dried, thereby obtaining the subject compound (101.5 g) as a white solid.

1. customAfter completion of the reaction
2. filtrationThe precipitated crystal was filtrated
3. washwashed with water
4. customdried