反应详情

The mixture was allowed to stand overnight and was transferred to a separatory funnel and acidified with 125 ml concentrated hydrochloric acid. The organic layer was separated and the water layer extracted three times with 50 ml diethyl ether. The extracts were combined with the organic layer, dried through sodium sulfate, and the diethyl ether was removed by means of a Rotovap. 182 Grams of product were obtained which when analyzed by GC indicated 83.6% lactone and 7.8% ethyl acetoacetate.

1. customwas transferred to a separatory funnel
2. customThe organic layer was separated
3. extractionthe water layer extracted three times with 50 ml diethyl ether
4. dry with materialdried through sodium sulfate
5. customthe diethyl ether was removed by means of a Rotovap
6. custom182 Grams of product were obtained which when