Methyl p-toluenesulfonate → HCID 15052180, compound

HRID 2081495Notes

Reaction equation

HRID 2081495 reaction equation
[CH3:1][N:2]1[CH2:7][CH2:6][CH2:5][CH2:4][CH:3]1[CH2:8][OH:9].[C:10]1([CH3:21])[CH:15]=[CH:14][C:13]([S:16]([O:19]C)(=[O:18])=[O:17])=[CH:12][CH:11]=1>>[C:10]1([CH3:21])[CH:11]=[CH:12][C:13]([S:16]([O-:19])(=[O:17])=[O:18])=[CH:14][CH:15]=1.[CH3:1][N+:2]1([CH3:10])[CH2:7][CH2:6][CH2:5][CH2:4][CH:3]1[CH2:8][OH:9]

Participants

3

Reactant 2

HCID 6645Methyl p-toluenesulfonateHCID 893941-Methyl-2-piperidinemethanol

Product 1

HCID 15052180HCID 15052180, compoundYield 157.1%

Procedure

The procedures of Reference Example 3 were repeated using 2.58 g of 1-methyl-2-piperidinemethanol and 3.72 g of methyl p-toluenesulfonate to give 4.95 g of the desired compound.

Sources & evidence

ORD record
ord-0eb2698c0d9b427c98860b8dca9e45c2
Source dataset
uspto-grants-1993_02
Patent number
US05183811

Reaction notes

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