Water → HCID 19779078, compound

HRID 2081940Notes

Reaction equation

HRID 2081940 reaction equation
[Cl-].[NH4+].O.[CH3:4][S:5]([C:8]1[CH:13]=[CH:12][C:11]([O:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH3:26])=[C:10]([N+:27]([O-])=O)[CH:9]=1)(=[O:7])=[O:6]>[Fe].C(O)(C)C>[NH2:27][C:10]1[CH:9]=[C:8]([S:5]([CH3:4])(=[O:6])=[O:7])[CH:13]=[CH:12][C:11]=1[O:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH3:26]

Participants

6

Reactant 3

HCID 962WaterHCID 25517Ammonium ChlorideHCID 67854994HCID 67854994, compound

Product 1

HCID 19779078HCID 19779078, compound

Reagents, catalysts & solvents 2

HCID 23925IronCatalystHCID 3776IsopropanolSolvent

Procedure

A mixture of 25.2 g of iron powder, 1 g of ammonium chloride, 25 ml of water and 250 ml of isopropanol was heated and stirred in a nitrogen stream. To the mixture 23.1 g of dodecyl 4-methylsulfonyl-2-nitrophenyl ether was added. After the conclusion of the addition and a 1-hour stirring, the resulting solution was filtrated out by a Nusche coated sellaite therein. The reaction mixture was concentrated, and to the mixture methanol was added to deposit 17.5 g of dodecyl 2-amino-4-methylsulfonylphenyl ether crystal.

Workup

  1. temperaturewas heated
  2. additionAfter the conclusion of the addition
  3. stirringa 1-hour stirring
  4. filtrationthe resulting solution was filtrated out by a Nusche coated sellaite
  5. concentrationThe reaction mixture was concentrated
  6. additionto the mixture methanol was added

Sources & evidence

ORD record
ord-d341078c46b6475da0572d628786e092
Source dataset
uspto-grants-1993_02
Patent number
US05187055

Reaction notes

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