Triethylamine → HCID 131717757, compound

HRID 2082128Notes

Reaction equation

HRID 2082128 reaction equation
Cl.[NH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][N:9]1[C:13](=[O:14])[C:12]2[CH:15]=[C:16]([N+]([O-])=O)[CH:17]=[CH:18][C:11]=2[S:10]1.C(N(CC)CC)C.[CH3:29][O:30][CH:31]=[CH2:32].[CH:33]1[C:38](=[O:39])[O:37][C:35](=[O:36])[CH:34]=1>CN(C=O)C.O>[CH3:29][O:30][CH:31]=[CH2:32].[CH:33]1[C:38](=[O:39])[O:37][C:35](=[O:36])[CH:34]=1.[NH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][N:9]1[C:13](=[O:14])[C:12]2[CH:15]=[CH:16][CH:17]=[CH:18][C:11]=2[S:10]1

Participants

6

Reactant 3

HCID 8471Triethylamine2×HCID 62708Furan-2,5-dione--methoxyethene (1/1)HCID 19779120HCID 19779120, compound

Product 1

HCID 131717757HCID 131717757, compound

Reagents, catalysts & solvents 2

HCID 962WaterSolventHCID 6228DimethylformamideSolvent

Procedure

A solution of 1.0 g (3 mmol) of the above synthesized N-(6-aminohexyl)-5-nitrobenzoisothiazol-3-one hydrochloride in 25 mL of was prepared and 0.83 mL (5.9 mmol) of triethylamine added. This was added dropwise to a mixture of 0.89 g (6 mmol of anhydride) of Gantrez AN 119 (M.W. 20,000, GAF Corp.) in 15 mL of DMF. After stirring for 30 min, another 0.41 mL (3 mmol) of triethylamine in 45 mL of H2O was added and the mixture stirred for 30 min.

Workup

  1. customof was prepared
  2. stirringthe mixture stirred for 30 min.

Sources & evidence

ORD record
ord-cda3a6d6ea014965bcba2743a35e6cfe
Source dataset
uspto-grants-1993_02
Patent number
US05187265

Reaction notes

Loading…