Ethanol → 2-Chloro-4-ethoxy-6-dimethylamino-1,3,5-triazine

HRID 2082641Notes

Reaction equation

HRID 2082641 reaction equation
[Na].ClC1N=NN=C(Cl)C=1.[Cl:10][C:11]1[N:16]=[C:15](Cl)[N:14]=[C:13]([N:18]([CH3:20])[CH3:19])[N:12]=1.[CH2:21]([OH:23])[CH3:22]>>[Cl:10][C:11]1[N:16]=[C:15]([O:23][CH2:21][CH3:22])[N:14]=[C:13]([N:18]([CH3:20])[CH3:19])[N:12]=1

Participants

5

Reactant 4

HCID 702Ethanol2×HCID 169852,4-Dichloro-6-(dimethylamino)-1,3,5-triazineHCID 5360545SodiumHCID 18348308Dichlorotriazine

Product 1

HCID 233381422-Chloro-4-ethoxy-6-dimethylamino-1,3,5-triazine

Procedure

A solution of sodium (0.46 g.) in ethanol (50 ml.) was added with stirring and waterbath cooling (25° C) to a solution of the dichlorotriazine (3.86 g.) from (a) in ethanol (50 ml.). Following the addition the solution was poured into ice water (250 ml.) and the product collected, dried and crystallised from petroleum as needles (2.5 g.) having a melting point of 124° C.

Workup

  1. additionthe addition the solution
  2. customthe product collected
  3. customdried
  4. customcrystallised from petroleum as needles (2.5 g.)

Sources & evidence

ORD record
ord-8330b79918314c6099f0d8671bbfa67d
Source dataset
uspto-grants-1978_04
Patent number
US04082536

Reaction notes

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