Pyridine → HCID 12246538, compound

HRID 2082936Notes

Reaction equation

HRID 2082936 reaction equation
[C:1]1([C:7](=[N:13][NH2:14])[C:8]2[S:9][CH:10]=[CH:11][CH:12]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.N1C=CC=CC=1.C(OO)(=O)C>CN(C)C(=O)C.C(O)(=O)C>[C:1]1([C:7]([C:8]2[S:9][CH:10]=[CH:11][CH:12]=2)=[N+:13]=[N-:14])[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1

Participants

6

Reactant 3

HCID 1049PyridineHCID 6585Peracetic AcidHCID 238592HCID 238592, compound

Product 1

HCID 12246538HCID 12246538, compound

Reagents, catalysts & solvents 2

HCID 176Acetic AcidSolventHCID 31374DimethylacetamideSolvent

Procedure

To a mixture of phenyl-2-thienyl ketone hydrazone (20.2 g; 0.1 mole), and pyridine (24.8 ml; 0.307 mole) in N,N-dimethylacetamide (100 ml) stirred and cooled to 15° was added peracetic acid (17.7 ml of a 38% w/w solution in glacial acetic acid; 0.1 mole) during 40 minutes, the temperature being maintained at +15° throughout.

Workup

  1. temperaturecooled to 15°
  2. temperaturethe temperature being maintained at +15° throughout

Sources & evidence

ORD record
ord-e06efc0682284a90832d45e4d164069e
Source dataset
uspto-grants-1978_04
Patent number
US04083837

Reaction notes

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