Diethyl Ether → HCID 20359121, compound

HRID 2083029Notes

Reaction equation

HRID 2083029 reaction equation
[C:1]([NH:4][S:5]([C:8]1[CH:9]=[C:10]([C:15](=[O:18])[CH2:16][Br:17])[CH:11]=[CH:12][C:13]=1[Cl:14])(=[O:7])=[O:6])(=[O:3])[CH3:2].[CH2:19]([NH:21][C:22]([NH:24][CH2:25][CH:26]([O:28][CH3:29])[CH3:27])=[S:23])[CH3:20].CCOCC>C(OCC)(=O)C>[BrH:17].[C:1]([NH:4][S:5]([C:8]1[CH:9]=[C:10]([C:15]2([OH:18])[CH2:16][S:23][C:22](=[N:24][CH2:25][CH:26]([O:28][CH3:29])[CH3:27])[N:21]2[CH2:19][CH3:20])[CH:11]=[CH:12][C:13]=1[Cl:14])(=[O:7])=[O:6])(=[O:3])[CH3:2]

Participants

5

Reactant 3

HCID 3283Diethyl EtherHCID 20359072HCID 20359072, compoundHCID 22760509HCID 22760509, compound

Product 1

HCID 20359121HCID 20359121, compound

Reagents, catalysts & solvents 1

HCID 8857Ethyl AcetateSolvent

Procedure

3.7 g (0.01 mol) of 3'-acetylsulfamoyl-2-bromo-4'-chloroacetophenone are stirred at 20° C during 24 hours in 20 ml of ethyl acetate with 1.8 g (1.01 mol) of 1-ethyl-3-(2-methoxypropyl)thiourea, 60 ml of ether are added and the amorphous oily precipitate is solidified by trituration after under 40 ml of ether decanting the solvent. Amorphous solid substance capable of flowing, decomposition starting at 65° C.

Workup

  1. additionare added
  2. customstarting at 65° C.

Sources & evidence

ORD record
ord-416720ec627f41948ec9ef9a872d5a22
Source dataset
uspto-grants-1978_04
Patent number
US04083979

Reaction notes

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