Ethanesulfonyl chloride → HCID 178477734, compound

HRID 2083949Notes

Reaction equation

HRID 2083949 reaction equation
C(OC([NH:11][C@H:12]([C:20]([OH:22])=O)[CH2:13][CH2:14][CH2:15][NH:16][C:17](=[NH:19])[NH2:18])=O)C1C=CC=CC=1.[CH2:23]([S:25]([Cl:28])(=[O:27])=[O:26])[CH3:24].[NH:29]1[CH2:33][CH2:32][CH2:31][CH2:30]1>>[ClH:28].[NH:19]=[C:17]([NH:18][S:25]([CH2:23][CH3:24])(=[O:27])=[O:26])[NH:16][CH2:15][CH2:14][CH2:13][C@@H:12]([C:20]([N:29]1[CH2:33][CH2:32][CH2:31][CH2:30]1)=[O:22])[NH2:11]

Participants

4

Reactant 3

HCID 11667Ethanesulfonyl chlorideHCID 31268PyrrolidineHCID 178512917HCID 178512917, compound

Product 1

HCID 178477734HCID 178477734, compound

Procedure

Starting from (S)-N2-(benzyloxycarbonyl)-arginine, ethanesulphonyl chloride and pyrrolidine, the expected product is obtained according to the procedure described in Example 1.

Sources & evidence

ORD record
ord-1485507f83d740cd854e22b9b4885df9
Source dataset
uspto-grants-2004_04
Patent number
US06716843B2

Reaction notes

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