Pyridine → HCID 22733447, compound

HRID 2084560Notes

Reaction equation

HRID 2084560 reaction equation
[C:1](Cl)(=[O:6])[C:2]([CH3:5])([CH3:4])[CH3:3].Cl.O[C:10]1[CH:16]=[C:15]([OH:17])[CH:14]=[CH:13][C:11]=1[NH2:12].N1C=CC=CC=1>C1CCCCC1.C(OCC)(=O)C>[C:2]([C:1]1[O:6][C:10]2[CH:16]=[C:15]([OH:17])[CH:14]=[CH:13][C:11]=2[N:12]=1)([CH3:5])([CH3:4])[CH3:3]

Participants

6

Reactant 3

HCID 1049PyridineHCID 62493Pivaloyl chlorideHCID 134088224-Aminobenzene-1,3-diol hydrochloride

Product 1

HCID 22733447HCID 22733447, compound

Reagents, catalysts & solvents 2

HCID 8078CyclohexaneSolventHCID 8857Ethyl AcetateSolvent

Procedure

A mixture of 1.01 ml of pivaloyl chloride, 808 mg 2,4-dihydroxyaniline hydrochloride (formula V) and 0.4 ml of pyridine is heated at about 210° for about 18 hours. The mixture obtained is dispersed in a mixture of cyclohexane and ethyl acetate and purified by chromatography. The title compound is obtained (m.p. 204-210°).

Workup

  1. temperatureis heated at about 210° for about 18 hours
  2. customThe mixture obtained
  3. custompurified by chromatography

Sources & evidence

ORD record
ord-7732a6878de642618b62e9ac97ff4b2c
Source dataset
uspto-grants-2004_04
Patent number
US06716865B1

Reaction notes

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