Pentane → HCID 22731334, 화합물

HRID 2085587노트

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HRID 2085587 반응식
Br[C:2]1[CH:3]=[C:4]([CH2:13][CH:14]2[CH2:19][CH2:18][CH2:17][CH2:16][CH2:15]2)[C:5]2[O:9][CH2:8][C:7]([CH3:11])([CH3:10])[C:6]=2[CH:12]=1.C([Li])(C)(C)C.CCCCC.[B:30](OC)([O:33]C)[O:31]C>C(OCC)C>[CH:14]1([CH2:13][C:4]2[C:5]3[O:9][CH2:8][C:7]([CH3:11])([CH3:10])[C:6]=3[CH:12]=[C:2]([B:30]([OH:33])[OH:31])[CH:3]=2)[CH2:19][CH2:18][CH2:17][CH2:16][CH2:15]1

참가 물질

6

반응물 4

HCID 8003PentaneHCID 8470Trimethyl borateHCID 22731332HCID 22731332, 화합물2회HCID 178418306HCID 178418306, 화합물

생성물 1

HCID 22731334HCID 22731334, 화합물

시약·촉매·용매 1

HCID 3283Diethyl Ether용매

실험 절차

Following General Procedure A and using 5-bromo-7-cyclohexylmethyl-3,3-dimethyl-2,3-dihydro-benzofuran (Intermediate 46, 0.58 g, 1.79 mmol),15 mL of anhydrous diethyl ether, 1.7M solution of t-butyllithium in n-pentane (2.21 mL, 3.77 mmol) and trimethyl borate (0.42 mL, 3.77 mmol) the title compound was obtained as a foam that was used as such for the next step without purification and characterization.

출처 및 근거

ORD 기록
ord-6c13698a195f4b3ea25f70e016ba8ff7
출처 데이터셋
uspto-grants-2004_04
특허 번호
US06720423B2

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